IDENTIFICATION OF A CONTACT-DEPENDENT GROWTH INHIBITION (CDI) SYSTEM THAT REDUCES BIOFILM FORMATION AND HOST CELL ADHESION OF ACINETOBACTER BAUMANNII DSM30011 STRAIN

Acinetobacter baumannii is a multidrug-resistant nosocomial opportunistic pathogen that is becoming a major health threat worldwide.In this study, we have focused on the A.baumannii DSM30011 strain, an environmental isolate that retains machine-accessories many virulence-associated traits.We found that its genome contains two loci encoding for cont

It is not rare that newly hatched chicks remain without feed for about 24 to 48 h before they are placed on farms due to a series of logistic operations.Furthermore, the spread in hatching time can also mount up to 30 to 48 h for late v.early hatchers.In other words, the practice is a complex combination of spread of hatch and delayed feed access.T

Gasdermin-D (GSDMD) is the ultimate effector of pyroptosis, a form of Pants programmed cell death associated with pathogen invasion and inflammation.After proteolytic cleavage by caspases, the GSDMD N-terminal domain (GSDMDNT) assembles on the inner leaflet of the plasma membrane and induces the formation of membrane pores.We use atomistic molecula

Benzo[a]pyrene (B[a]P), a highly carcinogenic polycyclic aromatic hydrocarbon primarily formed during incomplete organic matter combustion, undergoes a series of hepatic metabolic reactions once absorbed into the body.B[a]P contributes to liver damage, ranging from molecular DNA damage to the onset and progression of various diseases, including Pan

The purpose of the study is to explore how the COVID-19 situation has affected the illegal retail market and drug use patterns.Three research questions were formulated: 1) What has been the COVID-19 impact on the retail illegal drugs market? 2) How has the pandemic impacted drug use patterns? 3) Are there trends that presumably would have an impact